Epidemiology and Etiology of Anaphylaxis

The occurrence of anaphylaxis in the early 1900s was largely due to the use of serum from animals immunized with various toxins or bacteria to treat human illness. Most were due to diphtheria antitoxin injection. In the antibiotic era, penicillin and sulfa drugs have become the leading causes of fatal anaphylaxis. In recent years, between […]

What is Anaphylaxis ?

The term anaphylaxis arose from the experiments of Richer and Portier in the early 1900s and meant the opposite of prophylaxis, i.e., a lack of protection rather than the expected immunity. Nevertheless, the reaction is indeed immune in nature and depends on the formation of IgE antibody, the immunoglobulin responsible for typical allergic reactions. The […]

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